Comprehensive Diagnostic Evaluation

We want to get to the root causes of symptoms and illnesses. This means understanding your history and health now and over time.

Visualizing Anatomy

Gut Evaluations

How can providers at Pearl use lab and blood testing tools to diagnose root-cause issues?

Hormone Profile

A woman’s fertility and ovulation are complex.

Completing a hormone profile requires several days of lab work and can be time intensive. But this gives us a look into your ovarian function and quality of ovulations. You will want to confidently identify peak day in order to begin a hormone series, and we can draw labs in our office or send orders to a LabCorp location convenient for you.

Lab Testing

A multifactorial approach will also test cultures and biopsies. For example, we may collect an endometrial biopsy (EMB) between Cycle Days 5-10 to check for inflammation and/or infection of the lining of the uterus.

Semen Analysis

Fertility stems from the overall health of the man and the woman together. It’s estimated that one in five cases of infertility involve a male-factor concern. Factors include low sperm count, poor sperm motility, and sperm shape or morphology.


As part of a semen analysis, an at-home collection kit along with a perforated condom is used for seminal collection during intercourse. This is an accurate method that most couples prefer.


How can we visualize anatomy and get to root causes?

Office Hysteroscopy

An in-office hysteroscopy is a minimally invasive diagnostic tool that lets your doctor see the inside of your uterus quickly and easily right in his or her office, without the need for general anesthesia in an operating room.

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    Doctors will insert a small 5mm camera through the cervix and into the uterus. Using a saline solution to expand the uterine cavity, they can identify abnormalities such as polyps, fibroids, adhesions, and inflammation of the uterine lining. Small polyps or adhesions may be treated in the office at that time, though sometimes more significant findings may need to be treated in a scheduled hospital procedure. Even in that case, the office hysteroscopy provides helpful information in advancing your treatment.

Advanced Pelvic Ultrasound

A pelvic ultrasound is a noninvasive diagnostic exam that visualizes pelvic organs and produces black and white sonographic images that are used to assess anatomy and structures within the female pelvis.

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    A pelvic ultrasound allows quick visualization of the female pelvic organs and structures including the uterus, cervix, and ovaries.


    Pelvic ultrasound may be performed using one or both of 2 methods:


    Transabdominal (through the abdomen). A transducer is placed on the abdomen using the conductive gel


    Transvaginal (through the vagina). A long, thin transducer is covered with the conducting gel and a plastic/latex sheath and is inserted into the vagina


    Most patients will receive a baseline pelvic ultrasound via internal vaginal ultrasound as part of their initial evaluation, which provides the opportunity to visualize the uterus and ovaries and the diagnosis of uterine masses or ovarian cysts. 


    How can you prepare for a pelvic ultrasound?


    For a transabdominal ultrasound, you’ll want to drink a minimum of 24 ounces of clear fluid at least one hour before your appointment. Do not empty your bladder until after the exam.


    For a transvaginal ultrasound, you should empty your bladder right before the procedure.



Follicle Study

A follicle study assesses ovarian function by monitoring follicle development with an ultrasound. This procedure helps to visualize follicle development, confirm ovulation, and diagnose ovulation dysfunction. This study can aid in diagnosing causes of infertility and/or timing trigger shots.

Saline Infused Sonohysterogram

A Saline-Infused Sonohysterogram (SIS) is a minimally invasive diagnostic procedure designed to provide clear insights into intrauterine health.


During this procedure, the physician infuses saline solution into the uterus with a small catheter while the sonographer completes a transvaginal ultrasound. This allows for detailed evaluation of the uterine cavity, possibly diagnosing fibroids, polyps, or cesarean scar defects. This procedure typically takes less than 30 minutes and is performed in our office.

Selective HSG

A Saline-Infused Sonohysterogram (SIS) is a minimally invasive diagnostic procedure designed to provide clear insights into intrauterine health.


During this procedure, the physician infuses saline solution into the uterus with a small catheter while the sonographer completes a transvaginal ultrasound. This allows for detailed evaluation of the uterine cavity, possibly diagnosing fibroids, polyps, or cesarean scar defects. This procedure typically takes less than 30 minutes and is performed in our office.